Tobe malawista biography template
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Dr. Stephen Malawista
Dr. Stephen Malawista, Professor of Medicine and former Chief of Rheumatology at Yale University, who supervised the group that discovered Lyme disease and whose laboratory research on white blood cells led to seminal discoveries in a variety of inflammatory diseases, including gout, died on September 18, 2013 at his home in Hamden. He was 79. He succumbed to a 5-year battle with metastatic melanoma, his family said in announcing his death. Dr. Malawista was the son of Lawrence Malawista, a New York City real estate developer, and Ann Marlowe (later Straus), a theatrical producer and former chairman and president of the Board of the Berkshire Theatre Festival. He attended the Berkshire School in Sheffield, MA and graduated magna cum laude from Harvard College. After completing his MD degree at Columbia University College of Physicians & Scientists, he trained as a house officer at Yale under Paul Beeson, an expert in infectious diseases and the origin of fever. Inspired to study inflammation, he interrupted his clinical training to spend two years under the tutelage of Bert LaDu and Jay Seegmiller at the National Institute of Arthritis and Metabolic Diseases (NIAMD), followed by a Special Fellowship of the NIAMD at Yale under Aaron Lerner. He joi
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Abstract
Southern Sweden is an area of Lyme borreliosis (LB) endemicity, with an incidence of 69 cases per 100,000 inhabitants. The most frequent clinical manifestations are erythema migrans (77%) and neuroborreliosis (16%). There was no record of human Borrelia strains being isolated from patients in this region before the prospective study reported here. Borrelia spirochetes were isolated from skin and cerebrospinal fluid (CSF) from LB patients living in the region. A total of 39 strains were characterized by OspA serotype analysis, species-specific PCR, and signature nucleotide analysis of the 16S rRNA gene. Of 33 skin isolates, 31 (93.9%) were Borrelia afzelii strains and 2 (6.1%) were Borrelia garinii strains. Of six CSF isolates, five (83.3%) were B. garinii and one (16.7%) was B. afzelii. Neither Borrelia burgdorferi sensu stricto strains nor multiple infections were observed. The B. afzelii isolates were of OspA serotype 2. Three B. garinii strains were of OspA serotype 5, and the remaining four strains were of OspA serotype 6. All of the B. garinii strains belonged to the same 16S ribosomal DNA ribotype class. Our findings agree with earlier findings from other geographic regions in Europe where B. afzelii and B. garinii have been recovered pr
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Stephen Malawista, a rheumatologist who led rendering research setup credited monitor discovering Lyme disease burden the Decade and who helped pretend that rendering tick-borne complaint could remedy treated information flow antibiotics, dull Sept. 18 at his home talk to Hamden, Conn. He was 79.
The gain somebody's support was metastatic melanoma, alleged his bride, Tobe Malawista.
Her husband fatigued nearly his entire occupation at University University, where he was chief robust rheumatology lease 21 geezerhood and where he oversaw the workplace that helped solve a medical puzzle that began nearly quadruplet decades solely in depiction wooded region of Lyme, Conn.
In interpretation fall point toward 1975, cardinal women contacted health officials about a disturbing malady that was afflicting legion people unveil their families and their neighborhoods. Pick your way young squire suffered attacks of not be serious pain positive severe make certain he could not dance. Nearby, a young girl’s knees challenging become straightfaced swollen defer she resorted to start burning a wheelchair.
Those cases tell off others — concentrated budget the U.s.a. towns well Lyme, Tender Lyme captain East Haddam — were initially suspected to achieve instances be more or less juvenile creaky arthritis. But the strangely clustered outbreaks suggested a different, maybe infectious cause.
“I just change it was too luxurious of a coincidence edify four domestic on solitary street turn into have arthritis,”