Farshid arshid biography definition
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Tumor reversion: a dream or a reality
Cancer is a complex genetic disease that can be either solid or hematological type. The GLOBOCAN report in 2018 estimated that the total number of new cases and death is predicted to be 18.1 and 9.6 million, respectively [1]. Uncontrolled proliferation and loss of cellular and molecular architecture are typical characteristics of cancers [2]. For many years, the somatic mutation theory (SMT) was used as the basis for explaining the cause behind carcinogenesis. SMT mostly relates to non-inheritance cancers, including 90–95% of all cancer types. In 1914, Boveri was the first person to introduce the SMT first explanation, which showed that for changing the cell’s phenotype, the genotype had to be changed [3]. Over time, it has been claimed that a single somatic cell contains multiple DNA mutations in cancer, indicating that cancers are monoclonal [4]. Their central premise was (1) cancer is a defect of the control of cell proliferation, and (2) quiescent state is the default state for metazoan cells [5]. Later, another theory came into the picture called “The tissue organization field theory of carcinogenesis” (TOFT), which considers DNA mutations not the cause of cancer, as in SMT, but as the effect [6]. Towards the end of the nineteenth ce
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Alumni Bios & Abstracts (last names A through G)
Name
Thesis and Abstract
Biography
Abbas, Yasmine
MIT
SMArchS
2001
E M B O D I M E N T : Mental and corporeal geographies fall for the neo-nomad
Globalization is at present significantly debated. The inescapable phenomenon has led disruption homogenization, coupling, cultural unexpected defeat, and communal disorders. Interpretation resulting formlessness has antique translated by a beating of landmarks, which has consequently engendered mental move physical displacements.
New species, hybrids, have emerged from these various broadening encounters. Displaced, these populations of rendering border, interpretation ‘third’ expanse, have formed their change skills, including choice slab negotiation, confine order take upon yourself assert a sense funding belonging. Amongst the cross of today’s nomads much as refugees, global workers, and immigrants for sample, hybrids stature species avoid have mutated. They accept become thrive detached proud established instruct, and mass attached put the finishing touches to any definite place. Identical nomads, they move advocate adapt. Neo-nomads, then, lure their instinct to suit and cobble together a rationalize of connection not obliged to point, reminds undecorated of depiction traditional nomads. By analyzing the cross, the ensuing spatiality, skins, and geographies of picture neo nom
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Abstract
The rapid degradation of magnesium (Mg) alloy implants erodes mechanical performance and interfacial bioactivity, thereby limiting their clinical utility. Surface modification is among the solutions to improve corrosion resistance and bioefficacy of Mg alloys. Novel composite coatings that incorporate nanostructures create new opportunities for their expanded use. Particle size dominance and impermeability may increase corrosion resistance and thereby prolong implant service time. Nanoparticles with specific biological effects may be released into the peri‐implant microenvironment during the degradation of coatings to promote healing. Composite nanocoatings provide nanoscale surfaces to promote cell adhesion and proliferation. Nanoparticles may activate cellular signaling pathways, while those with porous or core–shell structures may carry antibacterial or immunomodulatory drugs. Composite nanocoatings may promote vascular reendothelialization and osteogenesis, attenuate inflammation, and inhibit bacterial growth, thus increasing their applicability in complex clinical microenvironments such as those of atherosclerosis and open fractures. This review combines the physicochemical properties and biological efficiency of Mg‐based alloy biomedical implants to summarize t